Since 2012
Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong links between long-lasting pain, depression, inflammation, and rising hypertension risk. Source link
A new dual-light microscope lets researchers observe micro- and nanoscale activity inside living cells without using dyes. The system captures both detailed structures and tiny moving particles at once, providing a more complete view of cellular behavior. Its creators tested it by analyzing changes during cell death and were able to estimate particle size and refractive index. They hope to push the technique toward imaging particles as small as viruses. Source link
Scientists have revealed that Hawaiian monk seals produce far more underwater vocalizations than previously believed. Their newly discovered 25-call repertoire includes complex combinations and a rare foraging-related call. These findings highlight an intricate acoustic world unfolding beneath the waves. The research opens the door to better protection strategies as human-made ocean noise continues to rise. Source link
Scientists mapped the Bas63 bacteriophage in unprecedented detail, uncovering how its tail machinery infects bacteria. The structure reveals rare whisker-collar features and distant evolutionary ties reaching back billions of years. These insights could guide new phage therapies and innovations in medicine, agriculture, and industry. Source link
Researchers developed a new nano-micelle formulation, CBD-IN, that finally gets CBD into the brain effectively. In mice, it relieved neuropathic pain quickly and didn’t cause the usual movement or memory side effects. Surprisingly, the pain relief didn’t use typical cannabinoid receptors, instead calming abnormal nerve activity more directly. The findings hint at new avenues for treating chronic pain and neurological diseases. Source link
Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol cravings and liver injury. When this enzyme was blocked in mice, their drinking decreased and their livers showed far less damage. Source link
In Peru’s mysterious Pisco Valley, thousands of perfectly aligned holes known as Monte Sierpe have long puzzled scientists. New drone mapping and microbotanical analysis reveal that these holes may once have served as a bustling pre-Inca barter market—later transformed into an accounting system under the Inca Empire. Source link
Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The condition is heavily linked to diabetes, hypertension, and obesity, and often goes unnoticed until late stages. Many countries lack access to dialysis and transplants, leaving millions without adequate care. Source link
Scientists built a tiny clock from single-electron jumps to probe the true energy cost of quantum timekeeping. They discovered that reading the clock’s output requires vastly more energy than the clock uses to function. This measurement process also drives the irreversibility that defines time’s forward direction. The insight could push researchers to rethink how quantum devices handle information. Source link
Scientists are turning venom, radioisotopes, engineered proteins, and AI into powerful new tools against cancer. From Amazonian scorpions yielding molecules that kill breast cancer cells as effectively as chemotherapy, to improved fibrin sealants and custom-grown bioactive factors, researchers are pushing biotechnology into uncharted territory. Parallel teams are advancing radiotheranostics that diagnose and destroy tumors with precision, while others forge experimental vaccines that train the immune system using hybrid dendritic cells. Source link
Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, blood vessel function, and glucose control. The interference may stem from how metformin affects mitochondrial activity. Source link
Researchers have created one of the most detailed virtual mouse cortex simulations ever achieved by combining massive biological datasets with the extraordinary power of Japan’s Fugaku supercomputer. The digital brain behaves like a living system, complete with millions of neurons and tens of billions of synapses, giving scientists the ability to watch diseases like Alzheimer’s or epilepsy unfold step by step. The project opens a new path for studying brain function, tracking how damage spreads across neural circuits, and testing ideas that once required countless experiments on real tissue. Source link
Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments that keep the benefits of weight loss while reducing unwanted side effects. Source link
Researchers have rediscovered a long-lost Babylonian hymn from 1000 BCE, using artificial intelligence to piece together fragments scattered across the world. The hymn glorifies ancient Babylon’s beauty, prosperity, and inclusivity, even describing women’s priestly roles — a rarity in surviving texts. Once a school favorite, it now provides a rare glimpse into everyday life and beliefs of the city that once ruled the world. Source link
A specially engineered antibody that can infiltrate kidney cysts has shown the ability to block key growth signals driving polycystic kidney disease. Early mouse studies suggest it may halt or even reverse cyst expansion without harming healthy tissue. Source link
Cutting-edge simulations show that Enceladus’ plumes are losing 20–40% less mass than earlier estimates suggested. The new models provide sharper insights into subsurface conditions that future landers may one day probe directly. Source link
Researchers have discovered chemical traces of life in rocks older than 3.3 billion years, offering a rare look at Earth’s earliest biology. By combining advanced chemical methods with artificial intelligence, scientists were able to detect faint molecular patterns left behind long after the original biomolecules disappeared. Newly analyzed fossils, including ancient seaweed from Canada’s Yukon Territory, helped validate the method and deepen understanding of early ecosystems. Source link
Microplastics—tiny particles now found in food, water, air, and even human tissues—may directly accelerate artery-clogging disease, and new research shows the danger may be far greater for males. In mice, environmentally realistic doses of microplastics dramatically worsened plaque buildup, altered key vascular cells, and activated harmful genes linked to inflammation and atherosclerosis, all without changes to weight or cholesterol. Source link
Migratory birds that fill North American forests with spring songs depend on Central America’s Five Great Forests far more than most people realize. New research shows these tropical strongholds shelter enormous shares of species like Wood Thrushes, Cerulean Warblers, and Golden-winged Warblers—many of which are rapidly declining. Yet these forests are disappearing at an alarming pace due to illegal cattle ranching, placing both birds and local communities at risk. Source link
New measurements of radio galaxies reveal that the solar system is racing through the universe at over three times the speed predicted by standard cosmology. Using highly sensitive data from multiple radio telescope arrays, researchers uncovered a surprisingly strong dipole pattern—one that challenges longstanding assumptions about how matter is distributed across cosmic scales. The results echo similar anomalies seen in quasar studies, hinting that something fundamental about our universe’s structure or our motion through it may need rewriting. Source link
Historians have traced myths about the Black Death’s rapid journey across Asia to one 14th-century poem by Ibn al-Wardi. His imaginative maqāma, never meant as fact, became the foundation for centuries of misinformation about how the plague spread. The new study exposes how fiction blurred with history and highlights how creative writing helped medieval societies process catastrophe. Source link
A first-of-its-kind trial is testing adult stem cell transplants for advanced dry macular degeneration. Early results show the treatment is safe and can significantly improve vision, even in severely affected patients. Participants gained measurable sight improvements in the treated eye. Researchers are now monitoring higher-dose groups as the therapy advances toward later trial phases. Source link
Researchers discovered that copper oxide catalysts form metallic copper mid-reaction, triggering a dramatic boost in ammonia output. The insight offers a roadmap for designing cleaner, more efficient ammonia-production technologies. Source link
Scientists have uncovered a surprising second type of lion roar, using AI to decode vocal signatures with remarkable precision. This breakthrough sheds new light on how lions communicate and offers a powerful new tool for conservationists racing to protect shrinking populations. Source link
