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Science

New study shows rheumatoid arthritis begins long before symptoms

Rheumatoid arthritis begins years before pain ever appears, and scientists have now mapped the hidden immune battle that unfolds long before symptoms. By studying people with RA-linked antibodies over seven years, researchers discovered sweeping inflammation, malfunctioning immune cells, and even epigenetic reprogramming in cells that had never encountered a threat. These changes show that the body is preparing for autoimmune attack long before joints become damaged. Source link

Top Stories

Peers are just doing their job in scrutinising the assisted dying bill | Letters

Dr Lucy Thomas and Penelope Jenkins support the House of Lords’ examination of the bill, but Margaret Pelling says they seem to be blocking the legislation, not scrutinising it Simon Jenkins is right that the Lords should not kill legislation by procedural manoeuvre (Unelected Lords are blocking assisted dying: that’s a democratic outrage) . But peers are not playing games with the assisted dying bill; they are finally providing the independent scrutiny it has so far lacked. And the carefully crafted campaign slogans collapse under examination. Rather than addressing suffering, the bill makes no mention of it – let…

Space

Season 4, Episode 15 Looking For Life in Ancient Lakes

Watch a video version of this podcast. As the Perseverance Rover flies toward Jezero Crater on Mars, which once hosted water, astrobiologists are interested in places on Earth that are similar to the rover landing site. Kennda Lynch, scientist at the Lunar and Planetary Institute in Houston, Texas, has been doing fieldwork in an ancient lake location in Utah called the Pilot Valley Playa. In this episode she describes her recent discoveries and why she’s excited about Perseverance. She also explains how all life forms create waste products, even bacteria, that could leave tracers or “biosignatures” for scientists to…

Entertainment India

Delhi Crime S3 OTT Verdict (Week 2): Shefali Shah & Huma Qureshi’s Show Takes 10 Days To Surpass Only Debut Numbers Of Last Season!

Delhi Crime S3 OTT Verdict (Week 2): Shefali Shah & Huma Qureshi’s Show Picks Pace! ( Photo Credit – YouTube) Huma Qureshi and Shefali Shah’s Delhi Crime S3 has maintained a decent pace with its viewership as it enters the second week of streaming on Netflix. The crime drama is trending as the number 1 non-English film on Netflix in not one or two, but ten countries – India, Bangladesh, Bahrain, Sri Lanka, Maldives, Oman, Pakistan, Qatar, UAE, and Mauritius. The show has secured one of the top 10 spots on Netflix this week, in 14 countries! Season 2…

Entertainment Hollywood & Global

X-Files' Producer Reveals the Worst Alternative Title for His Hit New Apple TV Sci-Fi Series

Vince Gilligan has a third hit series on his hands following the debut of his AppleTV science fiction mind-bender Pluribus. However, it was a long road to actually titling the series. In a recent panel appearance at New York Comic Con moderated by Happy Sad Confused host Josh Horowitz, Gilligan revealed that the series went through a litany of potential titles before settling on its current moniker. According to Gilligan, “We were in a title desert for two or three years.” Understandably, the series’ science fiction high-concept is difficult to sum up in a single word or phrase, meaning…

Health

Mayo Clinic researchers identify a new stem cell patch to gently heal damaged hearts

A researcher uses a pipette to place stem cells into a multiwell plate, with an image of the cells shown beneath. PHOENIX — Mayo Clinic researchers have developed a pioneering method to mend damaged hearts without open-heart surgery, an advance that could one day transform the treatment of heart failure.  The new approach uses lab-grown heart tissue made from reprogrammed adult stem cells, delivered through a tiny incision rather than a surgically opened chest cavity. In preclinical testing, the stem cell patch restored heart function and improved healing. Wuqiang Zhu, Ph.D. “For patients with severe heart failure, there are very few options…

Fitness

Menopause and mental health: The science of the menopausal brain

Reviewed by Brian St. Pierre, MS, RD and Helen Kollias, PhD It’s like my thoughts were under a pile of garbage. On a Friday night, as my husband and I tried to figure out where to eat, a typical conversation would go like this: Me: Do you want to go to that restaurant? Him: What restaurant? Me: I can’t think of the name. We’ve eaten there before. It’s that place with the peanut shells on the floor? It’s next to… You know… It’s on that road where we used to take the dog to the vet. Do you know…

World

Labour MPs celebrate end of two-child benefit cap in Reeves’s budget

Abolition is popular with backbenchers and is expected to stabilise precarious positions of the PM and chancellor Labour MPs have publicly thrown their weight behind Rachel Reeves’s budget after she abolished the two-child benefit cap and unveiled a slate of progressive measures including a mansion tax. Backbenchers rallied round the prime minister and chancellor on Wednesday afternoon after Keir Starmer hailed the measures being announced as “a Labour budget with Labour values”. Continue reading… Source link